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Limitations of Ab Initio Predictions of Peptide Binding to MHC Class II Molecules

Figure 4

Performance of three ab initio structure based prediction methods and NetMHCIIpan using HLA DRB1*0101 as an example.

The prediction results of three methods applied to HLA DRB1*0101 binding data are shown in the ROC plot. The ROC curves were generated by plotting the true positive rate (y-axis) against the false positive rate (x-axis). The AUC values for the three methods were shown in parentheses.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0009272.g004