CXCR7 Functions as a Scavenger for CXCL12 and CXCL11
Figure 6
Uptake of CXCL12 by mouse heart valve.
The aortic heart valves of wild type mice internalize CXCL12 tagged with a fluorescent protein (CXCL12-mCherry, upper right, red dots marked with arrowheads). Uptake of CXCL12-mCherry is partially competed with unlabeled 1.5 µM CXCL12 (lower left), and is partially resistant to administration of 10 µM AMD3100 (lower right). Pictures were taken in the indicated area (white frame upper left).