Protein Antioxidant Response to the Stress and the Relationship between Molecular Structure and Antioxidant Function
Figure 8
Structural modifications produced by acrolein and glucose on the Antioxidant Capacity (AC) of albumin.
Acrolein and glucose partially glycated produce an increase in the AC of albumin of up to 4 times the control native albumin (white bars) value. The exposure of UV (254 nm, 1 and 3 minutes) induces significant increases of AC of albumin exposed with respect to the control. However, the change produced in native albumin was higher than that presented by modified ones. The table below the graph includes the average AC of control samples and treated with UV (values in table without SD), and in parentheses the number of times the antioxidant capacity (AC) of albumin samples were increased in relation to the respective control. Results are expressed as mean ± SD (n = 5). *P<0.005 vs. control native albumin without UV; **P<0.005 vs. control (without UV); ***p<0.001 vs. control (without UV). 1 Partially glycated as described in the Material and Methods section.