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Dexamethasone, Cerebrospinal Fluid Matrix Metalloproteinase Concentrations and Clinical Outcomes in Tuberculous Meningitis

Figure 3

CSF MMP-9 concentration and CSF neutrophil count are significantly correlated in early follow up samples.

Early follow-up CSF samples, taken a median of 5 days (range 3–8, n = 29) into anti-tuberculosis treatment, from patients with tuberculous meningitis were analyzed for correlation between absolute neutrophil count and MMP-9 concentration (measured by ELISA). The R2 value for the correlation was 0.52 (p<0.001). Patients who received placebo are represented by light grey circles and dexamethasone by dark grey circles.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0007277.g003