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Lipid Alterations in Experimental Murine Colitis: Role of Ceramide and Imipramine for Matrix Metalloproteinase-1 Expression

Figure 3

Induction of MMP-1- and MMP-10-mRNA in the intestinal epithelial cell line Caco-2 after generation of ceramide by exogenous SMase (0,1U/ml), as determined by affymetrix gene array analysis.

Data are presented as relative increase after 6h and 24h in comparison to untreated control. (n = 4; ***p<0.001)

Figure 3

doi: https://doi.org/10.1371/journal.pone.0007197.g003