Crosstalk between Spinal Astrocytes and Neurons in Nerve Injury-Induced Neuropathic Pain
Figure 7
Black bar represents the period during which behavioral test was performed daily. Grey bar represents the period when drugs or saline was injected once a day. Stars represent the time points when rats were sacrificed for immunohistochemistry. Intrathecal intubation was performed on rats and followed by 4-day recovery. Behavioral test was performed 1 d before SNL to provide baseline threshold. Drugs and saline were injected 4 h prior to SNL and once a day for 3 more times after SNL. Behavioral test was performed once a day from 4 h post SNL till POD 7. SNL: spinal nerve ligation, POD: post-operation day.