Navigation of Chemotactic Cells by Parallel Signaling to Pseudopod Persistence and Orientation
Figure 6
Pseudopod formation and chemotaxis in natural gradients.
A, pseudopod formation during a natural wave. The cAMP wave was calculated from published data [23], [37]. The sharp increase of cell speed at the start of the wave [23], [24] was used to align the cAMP wave with present observations. Cells extend split and de novo pseudopodia; indicated are de novo pseudopodia as fraction of all pseudopodia. B, the chemotaxis index during a cAMP wave. The data are obtained from 20 cells during 4 late waves, obtained from three independent movies [19].