HIV-1 Matrix Dependent Membrane Targeting Is Regulated by Gag mRNA Trafficking
Figure 1
Distinct intracellular distribution and assembly dynamics of Rev-dependent and PRE-dependent HIV-1 Gag.
293T cells were transfected with Rev-dependent (A) and PRE-dependent (B) HIV-1 Gag-GFP and monitored with time-lapse confocal microscopy. Images of different Z sections were overlaid to produce single extended-focus image for each time point. Arrays of individual frames from two time-lapse videos covering about 12 hr compare the distribution and assembly dynamics of Rev-dependent and PRE-dependent HIV-1 Gag.