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Eyes Wide Shut: Amygdala Mediates Eyes-Closed Effect on Emotional Experience with Music

Figure 5

Correlation analysis for the PFC ROIs.

(A) ‘Seed’ time courses defined separately for eyes open and closed are shown on the parts of unfolded hemispheres. ‘Seed’ time courses were used to compute a voxel-by-voxel fit for the (B) BA 47 and for the (C) BA 46/9. Note a strong connection of the amygdala to the BA 47. The color scale indicates significance level. R – right hemisphere, L – left hemisphere. (D) Correlated activity of the VPFC (BA 47) and amygdala in comparison to the correlated activity of the DLPFC (BA 46/9) and amygdala, corresponding to mental sets of eyes closed and open, respectively. Note a significant difference between correlation coefficients. (E–F) Co-activation analyses respectively to the emotional context in music. A statistical comparison between the co-activation in the negative and neutral conditions was performed for the BA47 (E) and BA 46/9 (F).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0006230.g005