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Identification of Novel Leishmania donovani Antigens that Help Define Correlates of Vaccine-Mediated Protection in Visceral Leishmaniasis

Figure 5

Prechallenge antigen-specific IgG isotype responses in BALB/c mice vaccinated with cationic liposomal antigens.

Ten days after last vaccination serum samples were collected and assayed for antigen-specific IgG1 and IgG2a antibodies by ELISA. Each sample was examined in duplicate. The results are shown as the mean absorbance values±S.E. of five individual mice per group, representative of two independent experiments with similar results. * p<0.001 in comparison to control groups as assessed by one-way ANOVA and Tukey's multiple comparison test.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0005820.g005