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Abnormalities in Osteoclastogenesis and Decreased Tumorigenesis in Mice Deficient for Ovarian Cancer G Protein-Coupled Receptor 1

Figure 11

Immunohistochemistry staining of melanoma tissue from WT and KO mice.

H & E staining of tumor sections for gross observation. Staining of tumor section with anti-CD31 (1∶50) for angiogenesis analysis. Staining of tumor section with anti-F4/80 (1∶75) to view macrophage infiltration. Representative positively stained cells were indicated by arrows. Scale bar = 100 µm.

Figure 11

doi: https://doi.org/10.1371/journal.pone.0005705.g011