A Mathematical Model for the Detection Mechanism of DNA Double-Strand Breaks Depending on Autophosphorylation of ATM
Figure 2
Simulation results of repair processes of DSBs.
(A) A time course of the numbers of DSBs and DSBCs with the time-dependent expectation (μ) and standard deviation (σ). The blue lines denote μ±σ. (B) The histogram of the numbers of DSBs and DSBCs at time t = 100[min]. In these figures, the maximum number of repair proteins . Other parameters are as defined in Table 1. Initial numbers of molecules are
, and
.