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Mu and Delta Opioid Receptors Oppositely Regulate Motor Impulsivity in the Signaled Nose Poke Task

Figure 1

The progression of each trial during phase 4 of the signaled nose poke task.

Each trial started with a 20 s ITI; responses during this period had no consequence. Nose pokes during the subsequent pre-CS period (VT 1–8 s) reinstituted the ITI. If mice refrained from responding during the pre-CS period the trial progressed to the 5 s cue presentation. Nose pokes in the pre-assigned reinforcement hole during the cue presentation turned off the cue and immediately elevated the sucrose dipper. Nose pokes in the non-reinforced hole had no consequence. CS = conditioned stimulus; ITI = inter-trial interval; VT = variable time.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0004410.g001