Nematode Homologue of PQBP1, a Mental Retardation Causative Gene, Is Involved in Lipid Metabolism
Figure 5
Generation of T21D12.3 -specific and T07A9.1 -specific mutant nematodes.
A) T21D12.3 is the strictly conserved homologue of mammalian PQBP1 possessing WW domain and C-terminal domain. The genome maps show deleted regions in the genome of T21D12.3 and T07A9.1 mutants. B) T07A9.1 possesses a homology only to C-terminal domain of PQBP1 and does not possess WW domain. The genome maps show deleted regions in the genome of T07A9.1 mutants.