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Stat3 and c-Myc Genome-Wide Promoter Occupancy in Embryonic Stem Cells

Figure 5

Stat3 binds developmentally repressed genes in ES cells.

Genome-wide analysis of Stat3 and c-Myc TF binding sites and histone H3 acetylation (AcH3) at developmentally repressed genes (Gata6, Gata3, Pax5, Sox21, and Lhx1). Moving average (MA) enrichment values adjusted to log2 are shown. Chromosome number, sequence position, and conservation are also indicated on the plot.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0003932.g005