A miRNA Signature of Prion Induced Neurodegeneration
Figure 2
Functional relationships of miRNA target genes involved in the ubiquitin-proteasome pathway and unfolded-protein response and cell death responses.
This diagram shows the direct (solid lines) and indirect (dashed lines) interactions reported for these putative target genes (grey shading) of miRNAs de-regulated in scrapie infection in mice. Biological network analysis was performed using Ingenuity Pathway Analysis (IPA).