Computational Modelling of Genome-Side Transcription Assembly Networks Using a Fluidics Analogy
Figure 1
Pathways of transcription complex assembly.
A, Simplified model of protein complex assembly on DNA. B, Two-branch model in which TFIID (D) and SAGA (S) compete to load TBP (T) onto DNA, which then goes on to form a pre-initiation complex (PIC).