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The C/H3 Domain of p300 Is Required to Protect VRK1 and VRK2 from their Downregulation Induced by p53

Figure 6

PCAF or C/H3Del33 do not compete with p300 or C/H3 in the protection of VRK1.

H1299 cells were transfected with the indicated amount of plasmids in different combinations. p300 was detected with an antibody anti-p300 at 1∶1000 dilution. PCAF, p300-C/H3 and p300-C/H3Del33 were detected with an anti-flag antibody.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0002649.g006