Metabolomic landscape of macrophage discloses an anabolic signature of dengue virus infection and antibody-dependent enhancement of viral infection
Fig 4
Dengue virus infection generally increases cellular carbohydrate contents.
A: heatmap of carbohydrate variants. The mean Z-score of sextuplicate in each group was shown. B: display of carbohydrate variants by DENV infection only or ADE infection in comparison with non-viral infection. The mean density of sextuplicate of each variant was shown. Blue dot: significantly decreased variants; red dot: significantly increased variants. C: distribution of significant carbohydrate variants under different infection conditions. D: scheme of interplay of carbohydrate variants in glycolysis and pentose phosphate pathways.