In vitro culture of freshly isolated Trypanosoma brucei brucei bloodstream forms results in gene copy-number changes
Fig 6
Gene copy numbers for original and cultured MAK65 and MAK98 A-F: Copy numbers plotted across the genome, details as in Fig 4.
G: The average read densities for DNA from rat-grown MAK98 were divided by those for MAK65 and plotted across the genome (panel D / panel A). The results are on a log scale. H: The average read densities for RNA from rat-grown MAK98 were divided by those for MAK65 and plotted across the genome. The results are on a log scale. Many differences are likely to be due to the differentiation state (Fig 1C and 1D) but MAK98 shows clear RNA over-representation from chromosome 5.