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How geographic access to care shapes disease burden: The current impact of post-exposure prophylaxis and potential for expanded access to prevent human rabies deaths in Madagascar

Fig 3

The network of patient presentations and estimates of annual bite incidence.

(A) at the district level for the national data and (B) commune level for the Moramanga data: circles with a black outline represent the total number of patients reporting to each clinic for which we have data. Color corresponds to the clinic catchment. Circles with a white outline are the total number of bites reported for that administrative unit (plotted as the centroid). Lines show which clinic those patients reported to, with the line width proportional to number of patients from that district reporting to the clinic; flows of less than 5 patients were excluded. Out-of-catchment reporting is indicated where points and line colors are mismatched. For panel (A) districts in catchments excluded due to lack of forms submitted by the clinic are colored in grey. For (B) the inset of Madagascar shows the location of the enlarged area plotted, which shows the district of Moramanga (outlined in black), all communes included in it’s catchment (red polygons), and other communes where bites were reported to colored by their catchment (C) The estimated average annual bite incidence from the national and Moramanga data plotted at the district scale (both datasets) and at the (D) commune scale (Moramanga dataset). Colors correspond to the clinic catchment, shape indicates the dataset, and the size of the point indicates the number of observations (i.e. the number of years for which data was available for the national data; note for Moramanga 33 months of data were used). The point lines indicate the range of estimated bite incidence for each district. Mapped administrative boundaries from OCHA via HDX (https://data.humdata.org/dataset/madagascar-administrative-level-0-4-boundaries, CC-BY-IGO).

Fig 3

doi: https://doi.org/10.1371/journal.pntd.0008821.g003