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Seroprevalence of antibodies against Chlamydia trachomatis and enteropathogens and distance to the nearest water source among young children in the Amhara Region of Ethiopia

Fig 1

Age-dependent seroprevalence of trachoma and enteropathogens in the Amhara region of Ethiopia.

Age-dependent seroprevalence curves were fitted using generalized additive models (GAM) with a cubic spline for age. Seropositivity cutoffs were derived using ROC curves, if available, or by fitting finite mixture models (S1 Fig). Seropositivity cutoffs could not be estimated for V. cholerae in this study, so seroprevalence curves are not shown. For pathogens with more than one antigen, positivity to either antigen was considered positive. IgG response measured in multiplex using median fluorescence units minus background (MFI-bg) on the Luminex platform on 2267 blood samples from 2267 children.

Fig 1

doi: https://doi.org/10.1371/journal.pntd.0008647.g001