An investigation into the role of chronic Schistosoma mansoni infection on Human Papillomavirus (HPV) vaccine induced protective responses
Fig 4
HPV specific IgG antibody responses in Optical densities for Group 1 Schisto.-infected+HPV, Group 2 Schisto/PZQ+HPV and Group 3 HPV-only.
Week 0 (pre-vaccination), Week 4 (4 weeks after the 1st vaccination), Week 6 (6 weeks after the 1st vaccination and 2 weeks after the 2nd dose), Week 8 (8 weeks after 1st dose and 4 weeks after 2nd dose). The experimental points represent the mean IgG OD of each group at each time point. Groups are compared to the control group (Group 3 HPV-Only). Values were considered statistically significant when p≤0.05 and assigned *p = 0.01–0.05 (group 2 vs group3), **p = 0.001 (group 1 vs group3).