Unveil the transcriptional landscape at the Cryptococcus-host axis in mice and nonhuman primates
Fig 3
KEGG analyses of C. neoformans-infected lung tissues from mice and monkeys.
(A) Significantly expressed transcripts were subjected to KEGG analyses using Clusterprofiler 3.6.0 and plotted. Values in blue are for monkey lungs and values in red are for mice lung tissues. The dashed line separates values that meet the significance test (p < 0.05) from those that do not. (B) Differentially expressed metal and bone homeostasis genes (arrows). Upward arrows indicate induction of gene expression, and downward arrows indicate repression of gene expression. Monkey genes are indicated by blue arrows, and mouse genes are indicated by purple arrows.