Further Assessment of Monkeypox Virus Infection in Gambian Pouched Rats (Cricetomys gambianus) Using In Vivo Bioluminescent Imaging
Fig 3
Luminescence of Gambian Pouched Rats (Cricetomys gambianus) infected with Monkeypox/Luc+ by intradermal (A) and intranasal (B) routes.
Total luminescence (p/s/cm3/str), an estimate of viral load, peaks in all animals between days 8 and 14 and returned to background levels by day 21 presumably in relation to viral load. The total luminescence of the negative control (GPR 51), taken at day 0, is shown as a dashed line (A), to estimate background luminescence of Gambian pouched rats. The total luminescence of the sentinel animal (GPR 7) is shown in B. It remained similar to that of the negative control.