Automated High-Content Assay for Compounds Selectively Toxic to Trypanosoma cruzi in a Myoblastic Cell Line
Fig 6
Representative curves of three independent experiments of BNZ, NFX, posaconazole and cyclohexymide normalized activity (%) against T. cruzi amastigotes per compound concentration (M) for each of the three assay outputs: ‘Am/Cell’ (blue), ‘%Infected’ (green) were normalized as described in [15]; ‘Cells’ (cytotoxic impact of the drugs; yellow) is expressed as percentage of live cells, considering non-treated T. cruzi infected wells as 100%.