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Protective Efficacy of a Plasmodium vivax Circumsporozoite Protein-Based Vaccine in Aotus nancymaae Is Associated with Antibodies to the Repeat Region

Figure 2

Onset and magnitude of antibody response to VMP001 is similar in both the low (15 µg) and high (50 µg) dose groups.

In the presence of a strong adjuvant formulation the differences in anti-VMP001 titers between the two immunized groups were not stastically significant (ns = p>0.05; 2-tailed Mann Whitney U test) at any timepoint. Data is represented as Box (25–75 percentile) and Whisker (minimum and maximum) plot with horizontal line at the median value.

Figure 2

doi: https://doi.org/10.1371/journal.pntd.0003268.g002