Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice
Figure 5
Neutrophil-recruiting chemokine expression during the infection.
Mice (4–5/group) were inoculated with O. tsutsugamushi Karp stain, as described in Fig. 1. Samples were collected from the liver (A), lungs (B) and spleen (C) at 0, 2, 6, and 10 dpi and analyzed via qRT-PCR for gene expression. Data are shown as the mean ± SEM in each group and presented as “relative mRNA levels” (after normalization to the house-keeping genes). *, p<0.05; **, p<0.01.