Alternative Oxidase Mediates Pathogen Resistance in Paracoccidioides brasiliensis Infection
Figure 3
PbAOX expression during infection of alveolar macrophages is essential to maintain fungal viability.
Fungal viability of cells growing in culture medium (w/o MH-S) and in the presence of non-activated (MH-S-na) or IFN-g-activated (MH-S-a) alveolar macrophages: A. PbWt yeast cells; B. PbWt conidia; C. PbAOX-aRNA yeast cells; D. PbAOX-aRNA conidia. * P<0.05 when compared with non-activated macrophages.