Increased CD4+/CD8+ Double-Positive T Cells in Chronic Chagasic Patients
Figure 3
Functional characterization of DP T cells from Chagasic patients and uninfected controls.
(A) Representative dot plot of perforin expression by CD4+/CD8+ T cells in chagasic patients (CP), healthy controls (HC) and non-chagasic cardiomyopathy (NCC) donors. DP T cells were selected as indicated in Figure 1A and the percentage of perforin positive cell is shown in each quadrant. (B) Percentages and average (line) of CD4+/CD8+ DP T cells expressing perforin in CP, HC and NCC donors. *p<0.05 by Kruskal Wallis.