Risks of specific congenital anomalies in offspring of women with diabetes: A systematic review and meta-analysis of population-based studies including over 80 million births
Fig 2
Forest plot of the RRs in population-based studies for maternal pre-gestational diabetes and the risk of overall congenital anomalies (RR = 1.99, 95% CI 1.82 to 2.17, I2 = 90.0%, P < 0.001).
Analytical weights are from random effects meta-analysis. Grey boxes represent study estimates; their size is proportional to the respective analytical weight. Lines through the boxes represent the 95% CIs around the study estimates. The diamond represents the mean estimate and its 95% CI. The vertical red dashed line indicates the mean estimate. CI, confidence interval; DL, DerSimonian and Laird random effects model; RR, relative risk.