The regulation of methylation on the Z chromosome and the identification of multiple novel Male Hyper-Methylated regions in the chicken
Fig 2
Four of the 19 Novel MHM regions present on the Z chromosome and their effects on gene expression.
Panes illustrate regions 1, 2, 9, 12 (selected as being representative of all the regions). Each pane consists of the following: i) The male:female methylation ratio for the 1kb methylation windows that make up the MHM region (each black dot represents the ratio at one methylation window). The red hashed line at the base indicates the average male:female methylation ratio (~1.7). ii) Male:female gene expression ratio is indicated by the blue dots, one for each gene in the region, with the ratio shown on the left-side y-axis, and the blue hashed line indicating the average male:female gene expression ratio on the Z chromosome (~1.2). iii) The number of correlations between each gene and the 1kb methylation windows that make up each MHM. The direction of the correlation (positive or negative) is indicated by the bar being above the line (positive, coloured turquoise) or below the line (negative, coloured purple). The number of correlations is indicated on each bar, whilst each gene name is given on the x-axis.