Two RNA binding proteins, ADAD2 and RNF17, interact to form a heterogeneous population of novel meiotic germ cell granules with developmentally dependent organelle association
Fig 10
Proposed model of ADAD2-RNF17 granule maturation.
Morphologically and molecularly distinct ADAD2-RNF17 granules (green and purple) as well as the IMC (orange) shown. Protein components of each granule listed. Dashed arrows indicate potential avenues of maturation. Solid arrows represent protein accumulation or loss. Potential functions for each granule population indicated in italics. MT–mitochondria, ER–endoplasmic reticulum.