Multi-omics analysis of glucose-mediated signaling by a moonlighting Gβ protein Asc1/RACK1
Fig 5
Sensitivity analysis of differentially expressed genes (s-DEGs) after glucose addition.
A) Venn diagram of subsets of s-DEGs, before and after glucose addition for each mutant (mutantH-mutantL) and wildtype (wtH-wtL). Upper semicircle shows up-regulated s-DEGs and lower semicircle shows down-regulated s-DEGs. Numbers in parenthesis are shared s-DEGs regulated in the opposite direction, placed in the area corresponding to the direction of regulation. Subset of s-DEGs used for ORA analysis that are B) shared and change in the same direction; C) unique to asc1; D) unique to gpa2; E) shared and change in the opposite direction. Listed are all pathways and their functional categories with adjusted p-value <0.05.