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Differential transcript usage in the Parkinson’s disease brain

Fig 2

qPCR validation of ZNF189 and BCHE relative transcript abundances in individuals with PD and controls.

A: Schematic representation of ZNF189 and BCHE transcript variants analysed by qPCR. qPCR primer positions are indicated by arrows. B: Comparison of relative transcript abundances for the genes ZNF189 and BCHE, obtained from RNASeq and qPCR. The upper row represents raw relative transcript abundances. Listed are only transcripts that remained after filtering. Data points are grouped by condition on the x-axis (PD vs CT). The three data points per group represent the three samples selected for qPCR. The lower row represents the results of qPCR analysis. Red lines show the mean of the respective group.

Fig 2

doi: https://doi.org/10.1371/journal.pgen.1009182.g002