TENET 2.0: Identification of key transcriptional regulators and enhancers in lung adenocarcinoma
Fig 5
CENPA, FOXM1 and MYBL2 are highly expressed in tumors and associated with poor patient survival.
(A) Boxplots of expression of CENPA, FOXM1 and MYBL2 in 453 TCGA LUAD and 21 adjacent normal samples. All three genes were significantly upregulated in LUAD. (B) Kaplan-Meier survival plots comparing differences in survival between samples with the highest and lowest quartiles of CENPA, FOXM1 and MYBL2 expression. Survival was compared using TCGA LUAD samples.