Specification of Drosophila neuropeptidergic neurons by the splicing component brr2
Fig 1
Expression of the Nplp1 and proFMRFa neuropeptides is lost in brr2 mutants.
(A) Schematic representation of proFMRFa and Nplp1 neuropeptide expression pattern in the VNC, in control and brr2 mutants. (B-C) Immunostaining for proFMRFa and Nplp1 in control (B) and brr2 mutant (C, brr209c117/brr13A036) embryo CNS at AFT. (D) Quantification of proFMRFa and Nplp1 expressing cells within the Ap cluster, in control and brr2 mutants (Pearson’s chi-squared test; n>54 Ap clusters per genotype; *** = p<0.001).