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Intermittent Stem Cell Cycling Balances Self-Renewal and Senescence of the C. elegans Germ Line

Fig 8

Population density influences intermittent cycling in a dauer pheromone dependent fashion.

(A) Brood size of fog-1 females that had been kept at low or high density, and then mated at day 4 of adulthood (for statistical tests see S7A Table). Error bars represent 83% confidence intervals. Asterisks indicate significance of Wilcoxon rank sum test p‑value. (B) The percentage of mitotic zones that were in the dormant phase during a 1 h EdU labeling period at either day 1 of adulthood (fog-1) or day 3 of adulthood (wild-type and daf-22) for worms that had been kept at low or high density. For statistical tests see S7B–S7D Table. Asterisks indicate significance of Fisher’s exact test p-value.

Fig 8

doi: https://doi.org/10.1371/journal.pgen.1005985.g008