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LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes

Fig 4

LncRNA-HIT peaks are significantly associated with multiple loci which respond to siRNA-mediated reductions in the lncRNA.

Values represent mean fold-change decrease in limb bud expression after siRNA treatments compared to scrambled siRNA controls from three independent assays. Standard deviation for these analyses is depicted in parentheses. p-values for the associated peaks is depicted by the transformation -10 log10 (p-value) as determined by MACS analysis. †Loci located in cis to the nascent LncRNA-HIT peak.

Fig 4

doi: https://doi.org/10.1371/journal.pgen.1005680.g004