The Red Queen Model of Recombination Hotspots Evolution in the Light of Archaic and Modern Human Genomes
Figure 3
Derived allele frequency (DAF) spectra of mutations leading to motifs loss in the human branch.
DAF of mutations affecting HM (purple bars) and CM (orange bars) along the human branch (green branch in Figure 1). Allele frequencies are extracted from 1000 genomes phase I, using all available populations [31]. Mutations count for each motif (F2 subset) is indicated (N).