Combinatorial Regulation of Meiotic Holliday Junction Resolution in C. elegans by HIM-6 (BLM) Helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 Nucleases
Figure 4
Absence of chiasmata on ‘dissociated bivalents’ revealed by HTP-3 staining.
(A) Projections of representative nuclei of diakinesis oocytes stained with α-HTP-3 antibody and DAPI. Open arrowheads indicate the linked chromosomes shown in close-ups. The upper right panels show SIM images of a representative ‘dissociated bivalents’ of an [slx-1; him-6] oocyte. Linked univalent are encircled in blue. Scale bars are shown in white (4 µm). (B) Schematic representation of the proximal germ line, spermatheca and early embryogenesis in the C. elegans germ line.