Interactions among Polycomb Domains Are Guided by Chromosome Architecture
Figure 7
Interactions are constrained by chromosome architecture.
(A) A schematic overview of the wild type and inverted chromosome 3. The wild type strain used in this study (w1118) is shown on top. Dashed lines indicate the annotated positions of the break points (BK1 and BK2) present in the inverted chromosome of In(3LR)sep (bottom). Sequences on the inverted left arm 3LIN are red and 3RIN blue. Positions of the baits are indicated. (B–C) Domainograms show interactions of Abd-B (B) and Antp (C) on the inverted third chromosome. Note that all domainograms are plotted in the wild type orientation, which allows direct comparison with wild type data (Figure 2B, 2C). The colors on the x-axes indicate location on inverted chromosome (red = 3LIN; blue = 3RIN). Exact positions of the break points are highlighted by dashed vertical lines. Rest of plot details are described in Figure 1B and Figure 2.