Genomic Selective Constraints in Murid Noncoding DNA
Figure 1
Mean Nucleotide Substitution Rates in Different Sequence Types
Substitution rates were estimated at all sites (dark bars) and non-CpG-prone sites (light bars). Intronic substitution rates were estimated from all intronic sites, excluding splice regions which were assumed to occur in the first 20 and last 40 bp. 95% confidence intervals were estimated by bootstrapping the dataset by 1-Mb block, 1,000 times.