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Modeling cell populations metabolism and competition under maximum power constraints

Fig 1

Energetic description of interacting cells stocks embedded in an organism.

The diagram shows competing cells stocks as determined by the main process of ATP production, biosynthesis, and by the antagonistic interaction. It shows the associated flows of dissipated and useful energy, the latter being able to generate feedback for self-regulation on a higher hierarchical scale. The flow of energy and resources directed toward the rest of the organism is reduced by the inflows of the sub-system of competing cells stocks. The picture represents the interaction of plasma cells at myelomas onset which we define as being the core of the representation of Multiple Myeloma in the energy system language.

Fig 1

doi: https://doi.org/10.1371/journal.pcbi.1011607.g001