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Cell to whole organ global sensitivity analysis on a four-chamber heart electromechanics model using Gaussian processes emulators

Fig 10

The effect of simulator parameters on ventricular pressure rise and decay rate.

Barplots of the total order effects of the input parameters, ranked from most to least important, for ventricular maximum and minimum derivatives. The red and blue bars indicate parameters that explain >90% of the output variance, the gray bars indicate parameters that explain up to 95% of variance, while the rest of parameters are not displayed. Red and blue indicate positive and negative interactions, respectively. When this resulted in more than 10 parameters, the number of parameters was limited to 10 or to the number of parameters explaining 90% of output variance.

Fig 10

doi: https://doi.org/10.1371/journal.pcbi.1011257.g010