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Filter inference: A scalable nonlinear mixed effects inference approach for snapshot time series data

Fig 13

Accepted simulated measurements during filter inference.

The figure shows the histograms over all accepted simulated measurements at t = 0.6 (blue) during inference with a Gaussian filter (left panel) and a Gaussian KDE filter (right panel) from the bottom panel in Fig 12. The data-generating measurement distribution is illustrated in black. A typical realisation of each filter is illustrated in red. The inset figure in the right panel shows a typical kernel (blue) placed on a simulated measurement (black cross) during the construction of the Gaussian KDE filter. The simulated measurement is placed at a tumour volume of 350 for illustration purposes. The scale of the kernel is taken from the filter realisation.

Fig 13

doi: https://doi.org/10.1371/journal.pcbi.1011135.g013