Inferring evolutionary trajectories from cross-sectional transcriptomic data to mirror lung adenocarcinoma progression
Fig 2
Construction of the progression model in TCGA-LUAD cohort.
A showed the progression constructed by using 314 candidate genes in the TCGA-LUAD dataset. The triangles, squares and stars represent the molecular subtype of LUAD. The molecular subtypes were identified using 314 candidate genes. The subcluters used for survival analysis are showed in different colors. B showed K-M survival analysis among different subclusters. The significance level was calculated using Log-rank test. C showed the result of ANOVA analysis among different pathological stages in three independent cohorts. The significance level was set as P<0.05.