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Age-dependent ventilator-induced lung injury: Mathematical modeling, experimental data, and statistical analysis

Fig 3

Average young and old transients.

The solid blue and red lines plotted within the corresponding shaded bands represent the mean response for the transients associated with each experimental group at each time point. The borders of the surrounding bands encompass the 10th and 90th percentile at each time point. M0%, M1%, and M2% represent the percentage of the macrophage activity that is M0, M1, and M2, respectively. These percentages along with the Ee variable were validated by the experimental data at 0 hours and 2 hours. Due to differences in scale, the variables N and AN also include overlays with just the young mean and percentiles plotted.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1011113.g003