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Ecological and evolutionary dynamics of cell-virus-virophage systems

Fig 7

Number of surviving cells.

The number of surviving cells at the end of the simulations increased as a function of the cell number and the simulation condition. Boxplots of the resulting distributions are shown to the left and the fitted GAMs are shown to the right. The highest levels of survival were observed for the PCD simulation, followed by virophage inhibition. The three intercepts are significantly different and the smoothing terms statistically significant for the neutral virophages and PCD to the level of p < 10−15. The smoothing term for the simulation with inhibitory virophages was significant to the level of p < 10−5. The normalised root mean squared error (RMSE) is 0.7% and the deviance explained is 76.8%. NV: neutral virophages, IV: inhibitory virophages, PCD: programmed cell-death.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1010925.g007