Calibrating spatiotemporal models of microbial communities to microscopy data: A review
Fig 3
Model calibration techniques for spatiotemporal models of microbial communities.
Manual fitting involves direct adjustment of parameter values to achieve qualitative agreement between model predictions and observations. Nonspatial calibration is often systematic (based on a goodness of fit function) but is based on experiments that do not incorporate the spatial features of the system. Spatial calibration, against spatially distributed data, can be systematic (SSE-based) but must rely on summary statistics collected from the data.